A vitamin is an organic compound needed in small quantities that cannot be made in cells. In human nutrition , most vitamins function as coenzymes after modification; for example, all water-soluble vitamins are phosphorylated or are coupled to nucleotides when they are used in cells.  Nicotinamide adenine dinucleotide (NAD + ), a derivative of vitamin B 3 ( niacin ), is an important coenzyme that acts as a hydrogen acceptor. Hundreds of separate types of dehydrogenases remove electrons from their substrates and reduce NAD + into NADH. This reduced form of the coenzyme is then a substrate for any of the reductases in the cell that need to reduce their substrates.  Nicotinamide adenine dinucleotide exists in two related forms in the cell, NADH and NADPH. The NAD + /NADH form is more important in catabolic reactions, while NADP + /NADPH is used in anabolic reactions.
I have spent the last five years of my life with a much improved diet and devoting time to various types of cleansing and detoxification. It may be the case that until now, I wasn’t ready for the liver gallbladder cleanse, and that my body needed that preparation time. That preparation time is different for everyone. Just realize that it does take time. If you aren’t willing to invest some time and money in your health to eliminate toxins and prevent diseases from developing in the future, you must also realize that the expense, misery, and duration of illness and disease to come could be tenfold of what you are experiencing now.