In patients with the adrenogenital syndrome, a single intramuscular injection of 40 mg every two weeks may be adequate. For maintenance of patients with rheumatoid arthritis , the weekly intramuscular dose will vary from 40 to 120 mg. The usual dosage for patients with dermatologic lesions benefited by systemic corticoid therapy is 40 to 120 mg of methylprednisolone acetate administered intramuscularly at weekly intervals for one to four weeks. In acute severe dermatitis due to poison ivy, relief may result within 8 to 12 hours following intramuscular administration of a single dose of 80 to 120 mg. In chronic contact dermatitis, repeated injections at 5 to 10 day intervals may be necessary. In seborrheic dermatitis, a weekly dose of 80 mg may be adequate to control the condition.
Keratoacanthoma or KA is a skin growth that is reasonably common and is swiftly growing. It typically appears as a dome-like lump on skin which is sun-exposed on light-skinned elderly as well as middle-aged individuals. It is frequently found at sites of prior trauma or injury. Many researchers believe that keratoacanthomas is the less severe type of “squamous cell carcinoma”. Most keratoacanthoma cause only nominal injury to the skin but some do act more antagonistically and can spread to lymphatic nodes. It is not associated with internal malignancy except in instances which are very rare and where multiple keratoacanthomas are linked with a disease process known as Muir-Torre syndrome.
Cicatricial alopecia is hair loss resulting from a condition that damages the scalp and hair follicle 7 ( Figure 5 ) . In addition to a bald spot, the scalp usually has an abnormal appearance. Plaques of erythema with or without scaling or pustules may be present. Conditions that can be associated with cicatricial alopecia include infections (., syphilis, tuberculosis, acquired immunodeficiency syndrome, herpes zoster), autoimmune disease (discoid lupus erythematosus), sarcoidosis, scalp trauma (., injuries, burns), and radiation therapy. 7