The most common side effects associated with fluticasone are headache , throat infection, nasal irritation, sneezing , cough , nausea , vomiting . Hypersensitivity reactions such as skin rash , itching , facial swelling, and anaphylaxis may occur. Some children may experience growth suppression when using fluticasone. A bloody nasal discharge ( nosebleed ) and septum perforation may occur. Fungal infection of the nose and throat, glaucoma , and cataracts are also associated with intranasal fluticasone.
Mometasone furoate increased chromosomal aberrations in an in vitro Chinese hamster ovary-cell assay, but did not increase chromosomal aberrations in an in vitro Chinese hamster lung cell assay. Mometasone furoate was not mutagenic in the Ames test or mouse- lymphoma assay, and was not clastogenic in an in vivo mouse micronucleus assay and a rat bone marrow chromosomal aberration assay or a mouse male germ -cell chromosomal aberration assay. Mometasone furoate also did not induce unscheduled DNA synthesis in vivo in rat hepatocytes.