I've always had a very high sex drive and can only assume very high test levels when I was younger. Was prescribed finasteride once I turned 18 (6 years ago) and quickly noticed hairgrowth. Started blasting test and I shit you not within a few WEEKS I had lost probably a good 3 months of progress. Switched to dutasteride 1mg/day and really have no difference in sex drive or anything really, I honestly don't think dht really matters if you have x10 normal test levels anyways. If you need boners try melanotan 2, its actually miserable lol.
Estradiol's efficacy seems to vary widely with the person and the particular vehicle: I was on transdermal patches for two years ( , 2 patches changed twice weekly – considered a "high" dose of 17-beta estradiol), and my levels mostly stayed around 100 pg/mL, and I needed 100mg spironolactone daily to keep my testosterone down. When I switched to injections of Estradiol Valerate, as I was "titrating up" my testosterone was unmeasurably low at the same E2 level my patches were delivering. (I had decided to drop spiro at the same time due to it's side effects: for me it seemed to be fogging my brain and inducing suicidal ideation.) Increasing the dosage had the effect of adding a cup-size to my breasts after about two months of injections, after two years of HRT, at age 53 and with b-cup breasts already. This story is not unusual in the community, and it led me to try this form of HRT.