Winstrol is hepatotoxic, and because of this, it should be used at the lowest effective dose for the shortest possible cycle. What’s more, you should consider using a supplement designed to provide some additional protection. Milk thistle is a highly recommended option; studies suggest it can provide an effective layer of protection when it is used for the entire length of your cycle. There are some other supplements on the market, such as Liver Care, which are blends of natural ingredients that have been shown to work together to prevent liver toxicity.
Drugs such as Nolvedex bind to the oestrogen receptors , therefore reducing the effects of the heightened oestrogen in the body. Such drugs do nothing to reduce the amount of oestrogen in the body; they merely reduce its effects via competition for the receptors . If the user wishes to reduce the amount of oestrogen they should look to drugs such as proviron and anastrozole , which are known as anti-aromatases - . they lower the conversion of the steroid to oestrogen and therefore reduces the overall amount of oestrogen present.